API, Natural and Nano Medicine

SLINTEC is at the forefront of research and development in natural medicine, nanomedicine, natural insect repellents, and active pharmaceutical ingredients (API). By utilizing the gifts of Mother Nature we hope to create solutions that would benefit the environment, people and society.

Active Pharmaceutical Ingredients (API)

SLINTEC has taken the initiative to establish Sri Lanka’s first program to synthesize active pharmaceutical ingredients (APIs) of high quality and economic value, in an attempt to minimize the cost of importation and to provide good quality medication for the Sri Lankan community.

SLINTEC conducts the API synthesis program in 3 main stages:

  • First, APIs are synthesized in small scale in a fully equipped laboratory, where we explore novel, more efficient and cost effective synthesis pathways for the pharmaceuticals.
  • The second stage involves the characterization of pharmaceuticals in the molecular recognition laboratory, where molecules are analyzed using Nuclear Magnetic Resonance (NMR) spectroscopy, Gas Chromatography Mass Spectrometry (GCMS) and Liquid Chromatography Mass Spectrometry (LCMS).
  • In the third stage, APIs are scaled up to kilogram quantities in a fully equipped Pilot Plant facility located at SLINTEC Technical Incubation Center. The plant is well-equipped and can produce up to 20-30 kg of pharmaceuticals per batch, it is also in the process of obtaining the GMP (Good Manufacturing Practice) certification.

All API programs in SLINTEC  are overseen by a team of highly qualified Senior Research Scientists, Post-Doctoral Fellows and Scientists.

Cancer nanomedicine

By using surface-modified biopolymeric nanoparticles we are capable of delivering natural compounds with cancer-fighting ability to a specific target location. The advancement of nanomedicine has improved the way cancer is handled and has allowed tumor sites to be directly targeted, making treatment faster and more effective. Nanoparticles allow a variety of compounds to be attached to them, such as organic extracts from local plants, and can be designed to breakdown to harmless byproducts. Nanomedicine is improving healthcare and our understanding of the human body.

Natural anticoagulants

SLINTEC has developed a series of plant-based pharma graded products that act as anticoagulants and antiplatelets which can be used to improve the wellbeing of people with the risk of thrombotic disease. We specialise in isolating active metabolites, all from natural compounds, that are responsible for preventing the formation of clots.

Natural insect repellents

SLINTEC develops natural insect repellent that is composed almost entirely of biodegradable fibers and essential oils. These repellents are not chemical based and therefore do not harm your skin.

Natural medicine encapsulation

SLINTEC is currently involved in encapsulating natural medicine by electrospinning and electrospraying of bio-compatible and bio-based polymers.